Caffeine Standard [700003233]

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Caffeine Standard [700003233]

The Caffeine Standard intended to be used as the main standard in numerous performance qualification kits. This kit is designed for use by a Waters certified engineer or user as part of a performance maintenance or qualification activity. Protocols in the use of this kit are available via the purchase of Waters qualification services or self directed qualification training and license. Caffeine can be easily detected by any UV/PDA system. It is commonly used in HPLC and UPLC, and is detectable using the ELSD and MS instruments. It is used as the main standard in numerous performance qualification kits. This stock solution can be diluted to perform linearity testing, or perform many of the series of tests listed in other system qualifications listed above for HPLC and UPLC.

The kit contains 10 mL of 1.000 mg/mL Caffeine as a simple caffeine stock solution in 100% acetonitrile.

Store at room temperature.

System Performance Standards Key

Set Up

Setup standards are used upon installation of a new system, start-up of a system which has been idle for a period of time, or to re-start a system that has been moved to a new location. These standards may include multiple components within a kit which allow step by step setup and calibration, or they can be single mixtures which will enable a full system assessment and initialization.


These standards can be used for instrument calibration. Calibration is usually performed at a frequency that minimizes the risk of being out of calibration, in addition to major events suc h as when the instrument is moved and upon any major repair. Calibration can be confirmed as often as your standard operating procedures recommend. Look for solutions to calibrate your MS mass accuracy and resolution, UV detector linearity, UV and Fluorescence detector wavelength accuracy, injector accuracy and precision, and solvent system flow rate accuracy.


Your system is comprised of many interdependent components working together. An issue with any one component can produce erroneous final results. All components performing correctly will produce results within an expected variability. Some of the system components include mobile phase, column, tubing, pumping, injecting, temperature controlling, detecting, data collection rate, and integration
parameters. An issue in any one of the components listed can affect your result.
Performance Check Standards should be utilized on a routine basis. This includes anytime a column is changed, a method is changed, the instrument is moved, or confirmation of system performance is desired. Confirming the performance of your system can be done on a system basis with suitability standards or per individual instrument component. Benchmark performance should be established after
calibration and confirmed regularly.


These Mass Spectrometry solutions are used routinely and are available for every ionization mode. Use the solution to optimize the mass spectrometer setting for optimal signal either manually or through Intellistart.


This product contains hazardous material which requires special freight handling. Additional charges may apply.

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