UPC2 QC Reference Material [186007950]

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UPC2 QC Reference Material [186007950]

The UPC2 Quality Control (QC)Reference Material provides convergence chromatographic performance information for both chiral and achiral modes. It is designed for use with all ACQUITY UPC2 Columns (including  Trefoil, Torus, and Viridis Columns). This four compound mixture was optimized with the following key chromatographic performance (inclusive of mobile-phase pH) factors in mind:
  • Compounds are well separated and cover a wide chromatographic elution range
  • Contains a chiral compound to test chiral separation power (trans-stilbene oxide)
  • Contains an ionizable compound, to test mass spectrometer performance (sulfamethoxazole 254 m/z)
  • All four compounds are compatible with UV detection
The UPC2 QC Reference Material is a mixture of:
  • 0.50 mg/mL  (+/-) trans-Stilbene oxide
  • 0.50 mg/mL  Thymine  
  • 0.50 mg/mL  Sulfamethoxazole 
  • 0.50 mg/mL Sulfamethizole 
In a 1 mL solution of 75:25 ACN:MeOH
Store refrigerated 2-5 °C. 


  • ACQUITY UPC2 Torus Column Screening Kit, 2.1 mm x 50 mm Columns (2-PIC, DEA, DIOL, 1-AA) 4/pk (176003579)
  • ACQUITY UPC2 Torus Column Method Development Kit, 3 mm x 100 mm Columns (2-PIC, DEA, DIOL, 1-AA) 4/pk (176003580)
  • ACQUITY UPC2 Trefoil Column Screening Kit, 2.1 mm x 50 mm Columns (AMY1, CEL1, CEL2) 3/pk (176003577)
  • ACQUITY UPC2 Trefoil Column Optimization Kit, 3 mm x 150 mm Columns (AMY1, CEL1, CEL2) 3/pk (176003578)
  • LCMS Certified Vials (600000668CV)
  • TruView LCMS Certified Vials (186005666CV)

System Performance Standards Key

Set Up

Setup standards are used upon installation of a new system, start-up of a system which has been idle for a period of time, or to re-start a system that has been moved to a new location. These standards may include multiple components within a kit which allow step by step setup and calibration, or they can be single mixtures which will enable a full system assessment and initialization.


These standards can be used for instrument calibration. Calibration is usually performed at a frequency that minimizes the risk of being out of calibration, in addition to major events suc h as when the instrument is moved and upon any major repair. Calibration can be confirmed as often as your standard operating procedures recommend. Look for solutions to calibrate your MS mass accuracy and resolution, UV detector linearity, UV and Fluorescence detector wavelength accuracy, injector accuracy and precision, and solvent system flow rate accuracy.


Your system is comprised of many interdependent components working together. An issue with any one component can produce erroneous final results. All components performing correctly will produce results within an expected variability. Some of the system components include mobile phase, column, tubing, pumping, injecting, temperature controlling, detecting, data collection rate, and integration
parameters. An issue in any one of the components listed can affect your result.
Performance Check Standards should be utilized on a routine basis. This includes anytime a column is changed, a method is changed, the instrument is moved, or confirmation of system performance is desired. Confirming the performance of your system can be done on a system basis with suitability standards or per individual instrument component. Benchmark performance should be established after
calibration and confirmed regularly.


These Mass Spectrometry solutions are used routinely and are available for every ionization mode. Use the solution to optimize the mass spectrometer setting for optimal signal either manually or through Intellistart.


This product contains hazardous material which requires special freight handling. Additional charges may apply.

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